We are currently looking for oncology pharmacists to join our team! If you are interested in joining ChemoExperts, please click here. Not interested? Hide this message.

Side Effect: Swelling of breast tissue (gynecomastia)

What is Swelling of breast tissue (gynecomastia)?

Swelling of breast tissue, also known as gynecomastia, is a condition characterized by the development of glandular breast tissue, resulting in breast enlargement.

It is caused by an imbalance of estrogen and testosterone hormones in the body, where there is an increase in estrogen and a decrease in testosterone.

What does Swelling of breast tissue (gynecomastia) look like?

The appearance of gynecomastia typically presents as a palpable, firm, mass under the nipple-areolar complex, with or without tenderness. Breast tissue may be affected in both breasts or just one and the increase in breast tissue size can range from small to large.

Who gets Swelling of breast tissue (gynecomastia)?

In patients with cancer, gynecomastia occurs more often in those who undergo hormonal therapy.

How to prevent Swelling of breast tissue (gynecomastia)

How to treat Swelling of breast tissue (gynecomastia)


1. Fagerlund A, Cormio L, Palangi L, et al. Gynecomastia in Patients with Prostate Cancer: A Systematic Review. PLoS One 2015;10(8):e0136094.

Ghadjar P, Aebersold DM, Albrecht C, et al. Treatment strategies to prevent and reduce gynecomastia and/or breast pain caused by antiandrogen therapy for prostate cancer: Statement from the DEGRO working group prostate cancer. Strahlenther Onkol 2020;196(7):589-597.

Created: April 26, 2024 Updated: April 26, 2024