We are currently looking for oncology pharmacists to join our team! If you are interested in joining ChemoExperts, please click here. Not interested? Hide this message.

Side Effect: Increased tear production (lacrimation)

What is Increased tear production (lacrimation)?

Increased tear production, also known as hyperlacrimation or epiphora, refers to the excessive secretion of tears from the eyes. Common causes include eye irritation and allergies.

However, increased tear production can also occur if:

What does Increased tear production (lacrimation) look like?

The symptoms of increased tear production may include:

Who gets Increased tear production (lacrimation)?

Cancer treatments that can cause increased tear production include:

How to prevent Increased tear production (lacrimation)

How to treat Increased tear production (lacrimation)

The treatment for increased tear production depends upon the underlying cause.

If increased tear production persists despite conservative treatment, there are several medical interventions that may be considered. These include: medications such as anticholinergics, botulinum toxin injections, or surgery to reposition the punctum or create a new drainage pathway.


1. Lee H, Yoon S, Baek S. Causes of Tearing in Patients With Chemotherapy: Meibomian Gland Dysfunction Versus Lacrimal Drainage Obstruction. J Craniofac Surg. 2023 Jul-Aug 01;34(5):e419-e423.

2. Stoicescu EA, Iancu RC, Popa Cherecheanu A, et al. Ocular adverse effects of anti-cancer chemotherapy. J Med Life. 2023 Jun;16(6):818-821.

3. Omoti AE, Omoti CE. Ocular toxicity of systemic anticancer chemotherapy. Pharm Pract (Granada). 2006 Apr;4(2):55-9.

Created: April 26, 2024 Updated: April 26, 2024